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Fibrosis is the formation of
excess fibrous connective tissue in an organ or tissue in a
reparative or reactive process. This is as opposed to
formation of fibrous tissue as a normal constituent of an
organ or tissue. Scarring is confluent fibrosis that
obliterates the architecture of the underlying organ or
tissue.
The term is also sometimes used to describe a normal healing
process,[1] but this usage is less common.
Types
|
Type |
Most common location(s) |
Circumscription |
Cellularity |
Vascularity and
nature of vessels |
Appearance ofcollagen |
Elastic fibers |
Picture |
|
Nuchal fibroma |
Nuchal region |
No |
Very low |
Very low |
Bundles of fibers |
Scant |
|
|
Collagenous fibroma |
Shoulder girdle, extremities |
Yes, by macroscopic appearance, but microscopically
infiltrative |
Increased but generally low |
Low |
Scant or absent |
Amorphous |
|
|
Fibroma of tendon sheath |
Distal extremities, especially the hand |
Yes |
Low to high |
Moderate to high, with some slitlike vessels |
Amorphous |
Absent |
|
|
Scar |
Variable |
Variable |
Low to high |
Variable |
Amorphous |
Scant to absent |
|
|
Elastofibroma |
Subscapular chest
wall |
No |
Low to moderate |
Low |
Amorphous |
Abundant and abnormal |
|
|
Desmoid-typefibromatosis |
Abdominal wall, shoulder girdle |
Yes, by macroscopic appearance, but microscopically
infiltrative |
Moderate |
Moderate, mildly dilated |
Amorphous |
Absent |
|
|
Keloid |
Upper part of back, deltoid, presternal, ear lobes |
No |
Some fibroblasts |
Low |
Amorphous thick eosinophilic bundles |
Scant or Absent |
|
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